Correction of stability curves in Hill-Meissner’s equation
نویسندگان
چکیده
منابع مشابه
Computational tools for fitting the Hill equation to dose-response curves.
INTRODUCTION Many biological response curves commonly assume a sigmoidal shape that can be approximated well by means of the 4-parameter nonlinear logistic equation, also called the Hill equation. However, estimation of the Hill equation parameters requires access to commercial software or the ability to write computer code. Here we present two user-friendly and freely available computer progra...
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The Hill coefficient is commonly used to estimate the number of ligand molecules that are required to bind to a receptor to produce a functional effect. However, for a receptor with more than one ligand binding site, the Hill equation does not reflect a physically possible reaction scheme; only under the very specific condition of marked positive cooperativity does the Hill coefficient accurate...
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ژورنال
عنوان ژورنال: Mathematics of Computation
سال: 1966
ISSN: 0025-5718
DOI: 10.1090/s0025-5718-1966-0187405-x